: Select the Device security tab on the left-hand menu.
The most common cause for Error 39 on Windows 10 and 11 is the security feature, which prevents many virtual USB drivers from loading. Open the Start menu and search for Windows Security . Navigate to Device security on the left-hand sidebar. Under Core isolation , click on Core isolation details . Switch the Memory integrity toggle to Off . Restart your computer for the changes to take effect. Secondary Fix: Registry Editor (Remove Filters) mastercam x72022 virtual usb bus error 39 fix
: Reboot your computer to apply the changes. The driver should now load without Error 39. Secondary Fix: Windows Registry (HVCI Disable) : Select the Device security tab on the left-hand menu
The Virtual USB Bus driver ( vusbbus.sys ) is test-signed. Windows blocks it unless test signing is on. Navigate to Device security on the left-hand sidebar