Rare, but possible. If your system drive is full or has file system errors, the installer cannot allocate space for the root folder.

Right-click your DAW (e.g., Cubase, Ableton, FL Studio) and select Run as Administrator

Soundtoys V5 Preset location, presets not saving and hardlinks

on this new folder (same as step 2).

Background applications (DAWs, audio routers, SoundID Reference, etc.) can lock the root folder.

Here’s what Lena did—and what you can try too: