You must have the disc in your DVD drive during the first run for legitimacy verification; after the first successful run, the disc is no longer required for gameplay.
: Many users search for "Biohazard 2 Sourcenext CD Key Full" because the original Japanese installer can be notoriously difficult to bypass or activate without the correct alphanumeric string. biohazard 2 sourcenext cdkey full
: Provides a full English translation, adds XInput controller support, and enables higher resolution options. You must have the disc in your DVD